Hidden Toxicity of Human Papillomavirus Vaccine Ingredients

The HPV vaccine has a long history of toxicity. More and more research demonstrates the reasons for this.

But there is more to the story! 😊

Recent publications originating from Italy, Japan, Australia, Columbia, India, Ireland, Denmark, Mexico, Norway, Sweden, Canada, France, the USA, and the United Kingdom have reported post-HPV vaccination phenomena that share overlapping clinical features with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME), fibromyalgia (FM), postural orthostatic tachycardia syndrome (POTS), complex regional pain syndrome (CRPS), small fiber neuropathy (SFN), and autonomic dysfunction (AD).

Typical symptoms include (but are not limited to) prolonged generalized fatigue, chronic headaches, widespread generalized pain, tremors, orthostatic fainting, postural tachycardia, alterations in gastrointestinal motility, gait disturbance, anxiety, paresthesia’s, sleep disturbance, learning impairment, difficulty in concentration, and other cognitive phenomena.

See these articles:

Blitshteyn S, Brinth L, Hendrickson JE, Martinez-Lavin M (2018) Autonomic dysfunction and HPV immunization: an overview. Immunologic Res 66: 744-754.

Holland M, Rosenberg KM, Iorio E (2018) The HPV vaccine on trial. Skyhorse Publishing, USA.

Ozawa K, Hineno A, Kinoshita T, Ishihara S, Ikeda SI (2017) Suspected adverse effects after human papillomavirus vaccination: a temporal relationship between vaccine administration and the appearance of symptoms in Japan. Drug Safety 40: 1219-1229.

Chandler RE, Juhlin K, Fransson J, Caster O, Edwards IR, et al. (2017) Current safety concerns with human papillomavirus vaccine: a cluster analysis of reports in VigiBase. Drug Safety 40: 81-90.

Martinez-Lavin M, Martinez-Martinez LA, Reyes-Loyola P (2015) HPV vaccination syndrome: a questionnaire-based study. Clin Rheumatol 34: 1981-1983.

Cervantes JL, Doan AH (2018) Discrepancies in the evaluation of the safety of the human papillomavirus vaccine. Mem Inst Oswaldo Cruz 113: e180063.

At first glance one might be inclined to implicate an adverse autoimmune reaction to HPV vaccine materials as the cause of this patient’s illness. After all, it is now well known that other vaccines, such as influenza and hepatitis B, have already been confirmed as potential initiators of various autoimmune disorders including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Guillain-Barre Syndrome (GBS).

Vadalà M, Poddighe D, Laurino C, Palmieri B (2017) Vaccination and autoimmune diseases: is prevention of adverse health effects on the horizon? EPMA J 8: 295-311.

To adequately answer the question of why Gardasil and Cervarix cause injury, one needs to become familiar with the non-antigenic ingredients in HPV vaccines.

Gardasil 4 and 9 vaccines contain an ingredient known as polysorbate 80 (PS 80), added as a surfactant and emulsifier. PS 80 is a sorbitan compound, but the manufacturing process to produce PS 80 also produces an end product in the soup mixture known as sorbitol. Sorbitol makes the final PS 80 product cloudy which, in turn, would make the vaccine cloudy.

So, in order to render the vaccine clear and colorless sorbitol is removed from PS 80 by adding amorphous silica (silicon dioxide) and organosiloxanes (organosilicones). A brand name product that performs the same function is Britesorb.

Silica has a long and sordid proven history of human toxicity. Organosiloxanes, with their artificial silicon carbon bonds that never occur in any living organism on earth, are also a mission impossible for humans to deal with.

Brawer AE (2017) Mechanisms of breast implant toxicity: will the real ringmaster please stand up. Int Ann Med 1: 249.

The toxicity of organosiloxanes is now a proven reality and is directly responsible for the multiple ailments in women suffering from the genuinely novel entity known as silicone gel-filled breast implant toxicity.

Brawer AE (2017) Mechanisms of breast implant toxicity: will the real ringmaster please stand up. Int Ann Med 1: 249.

Brawer AE (2017) Destiny rides again: the reappearance of silicone gel-filled breast implant toxicity. Lupus 26: 1060-1063.

Brawer AE (1998) Silicon and matrix macromolecules: new research opportunities for old diseases from analysis of potential mechanisms of breast implant toxicity. Med Hypotheses 51: 27-35.

Brawer AE (2017) Is silicone breast implant toxicity an extreme form of a more generalized toxicity adversely affecting the population as a whole? Int Ann Med 1: 347.

This toxicity has nothing to do with autoimmunity, but rather involves disruption of more than two dozen biochemical processes in the body. As an example, one of the degradation products of organosiloxanes is silicic acid, which readily crosses the blood brain barrier and chelates neurotransmitters such as dopamine.

Cognitive dysfunction is the expected outcome. Silanols (another degradation product of organosiloxanes) can biointegrate into the proteoglycan matrix macromolecule receptor for acetylcholine, thereby causing unchecked activity of the sympathetic arm of the autonomic nervous system (and hence, palpitations, or rapid heartbeat).

Silanols can readily donate a methyl group to any accumulated mercury already present in one’s body, thereby synthesizing methylmercury.

Enhanced DNA methylation can also easily occur, thereby altering epigenetic factors that, in turn, create disturbances in gene expression and the production of autoantibodies and cytokines. Latent viruses that one has acquired during his or her lifetime can be reactivated by a similar toxicity mechanism adversely affecting viral epigenetic control.

These types of aberrations can create secondary amplification loops which, in turn, often lead to erroneous impressions of primary infectious and autoimmune etiologies.

An ISCOM (immune stimulating complex) is another ingredient in HPV vaccine materials, whose function is to enhance humeral and cellular immune responses to the antigens in question.

ISCOMs contain saponins, which are surfactants and emulsifiers indigenous to a variety of edible plants. Saponins are capable of causing intense foaming activity in aqueous solutions, which is quite desirable when they are added to soaps, shampoos and detergents.

But when saponins are routinely utilized in beer production manufacturers add organosiloxanes to control the foaming activity. The implications for preventing HPV vaccines from “bubbling up” are obvious. There is a vast difference between ingestion of a toxin versus parenteral administration of a toxin. The Food and Drug Administration (FDA) has never required any consumer products containing organosiloxanes to have these compounds listed as ingredients on any labels (and this applies to organic foods as well).

This is because for many decades physical chemists have brainwashed biochemists into believing that organosiloxanes are chemically and biologically inert, a premise that is now known to be completely untenable.

Brawer AE (2017) Is silicone breast implant toxicity an extreme form of a more generalized toxicity adversely affecting the population as a whole? Int Ann Med 1: 347.

Brawer AE (2018) What do fibromyalgia, chronic fatigue syndrome, and dysautonomia have in common with systemic lupus erythematosus? Lupus: Open Access 3: 1.

Brawer AE (2018) Mechanisms of disease causation in chronic fatigue syndrome/myalgic encephalomyelitis. Nat Med J.

Organosiloxanes and their degradation products also adversely affect enzyme functions (and thereby substrates and metabolites), as well as membrane permeability, neuronal transmission, and mitochondria.

With regard to mitochondria, oxidative phosphorylation and the electron transfer system are disrupted because silicon behaves like a metal at times, thereby altering electromagnetic fields. This leads to deficiencies in energy production and energy utilization plus impairment of the mitochondrial-mediated cell danger response to other environmental contaminants (such as pesticides, phthalates, etc.).

Brawer AE (2018) Mechanisms of disease causation in chronic fatigue syndrome/myalgic encephalomyelitis. Nat Med J.

Naviaux RK (2018) Metabolic features and regulation of the healing cycle-a new model for chronic disease pathogenesis and treatment. Mitochondrion 46: 278-297.

Organosiloxane-induced mitochondrial dysfunction can thus be viewed as “the straw that broke the camel’s back” – it is analogous to one’s house being on fire, but the fire engines cannot get there. Extracellular spillage of damaged mitochondrial organelles readily triggers activation of both innate and adaptive immunity, creating another secondary amplification loop.

Organosiloxanes and their degradation products can biointegrate into life-sustaining matrix macromolecules, which then causes a host of biochemical disruptions. One such macromolecule, a glycosaminoglycan known as chondroitin sulfate, binds the pre-formed mediators of inflammation inside mast cells.

When chondroitin sulfate is modified by chemical biointegration inappropriate release of mast cell contents occurs, creating allergic chaos as well as stimulation of other cells to release their inflammatory mediators.

Giannotta G, Giannotta N (2018) Vaccines and neuroinflammation. Int J Public Health Safe 3: 163.

Kempuraj D, Selvakumar GP, Thangavel R, Ahmed ME, Zaheer S, et al. (2017) Mast cell activation in brain injury, stress, and post-traumatic stress disorder and Alzheimer’s disease pathogenesis. Front Neurosci 11: 1-15.

One example of the latter involves mast cell mediated activation of brain microglia to secrete their immune stimulating cytokines. Thus, we have yet another example of a secondary amplification loop, which has been referred to as neuroinflammation. Once again one could erroneously conclude that autoimmune mechanisms are the primary offenders.

Leukopenia and thrombocytopenia have been reported in some patients with HPV vaccine-induced illness.

Bizjak M, Bruck O, Kanduc D, Praprotnik S, Shoenfeld Y (2016) Vaccinations and secondary immune thrombocytopenia with antiphospholipid antibodies by human papillomavirus vaccine. Semin Hematol 53: 48-50.

Heavy metals, such as platinum and rubidium, are utilized in the polymerization manufacturing process of organosiloxanes, and they do not fall out of the soup mixture at the end. A multitude of pathologic clinical phenomena are known to occur from excessive exposure to heavy metals.

Brawer AE (2017) Mechanisms of breast implant toxicity: will the real ringmaster please stand up. Int Ann Med 1: 249.

Cervarix vaccine ingredients do not contain PS 80, but they do contain sodium dihydrogen phosphate dihydrate (SDPD), a pH buffer and emulsifier. SDPD is manufactured from sodium carbonate (soda ash), and purified sodium carbonate contains residues of silica (silicon dioxide). The true residual silica content of sodium carbonate can vary substantially depending on the assay used to measure it. ISCOMs also are present in Cervarix.

Why does HPV vaccine-induced illness encompass numerous overlapping clinical features described in patients with CFS/ME, FM, POTS, CRPS, SFN and AD?

Because over 60,000 organosiloxane compounds have been synthesized in the past eighty years, and they now contaminate every worldwide environmental compartment.

A recent publication has linked organosiloxane contamination to the ever-expanding reports of metabolic and biochemical disruptions inherent to vague syndromes like CFS/ME.

Brawer AE (2018) Mechanisms of disease causation in chronic fatigue syndrome/myalgic encephalomyelitis. Nat Med J.

The list of metabolic dysregulations and dysfunctional physiology in CFS/ME has now been expanded to include both transcriptome changes and hypothalamic dysfunction, abnormalities that can easily be caused by the organosiloxane-induced alterations of epigenetic and microglial functions outlined earlier in this report.

Sweetman E, Ryan M, Edgar C, MacKay A, Vallings R, et al. (2019) Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome. Int J Immunopath Pharmacol 33.

Mackay A, Tate WP (2018) A compromised paraventricular nucleus within a dysfunctional hypothalamus: a novel neuroinflammatory paradigm for ME/CFS. Int J Immunopath Pharmacol 32: 1-8.

Chronicity can easily become the norm for all of the above syndromes and illnesses due to (a) Organosiloxane interference with normal healing processes, and (b) The perpetuation of biochemical and epigenetic disruptions during cell division.

The controversy surrounding HPV vaccine-induced illness is no longer one of methodology, it is one of terminology. HPV vaccine-induced illness is a genuinely novel and legitimate entity unto itself that shares clinical features with the ever-expanding list of neurologic fatiguing syndromes.

This illness is undoubtedly caused by multiple toxic disturbances of the body’s biochemistry induced by emulsifiers, surfactants, and immune-stimulatory complexes.

 HPV vaccine-induced illness is not a psychogenic reaction fueled by the news media and attorneys.

Those reactions are real to the patients!

God bless y’all! 🙂

Dr. Serge

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